|Description:||Under a high magnification of 400X, this photomicrograph revealed some of the ultrastructural features displayed by a Clonorchis sinensis egg. C. sinensis is a trematode, or fluke, and is also known as the Chinese, or oriental liver fluke.|
Clonorchis sinensis eggs are small, ranging in size from 27µm to 35µm by 11µm to 20µm. The eggs are oval shaped with a convex operculum that rests on visible "shoulders," at the smaller end of the egg. At the opposite (larger, abopercular) end, a small knob or hooklike protrusion is often visible. The miracidium is visible inside the egg.
Clinical Features:Most pathologic manifestations result from inflammation and intermittent obstruction of the biliary ducts. In the acute phase, abdominal pain, nausea, diarrhea, and eosinophilia can occur. In long-standing infections, cholangitis, cholelithiasis, pancreatitis, and cholangiocarcinoma can develop, which may be fatal.
Laboratory Diagnosis:Microscopic demonstration of eggs in the stool or in duodenal aspirate is the most practical diagnostic method. The adult fluke can also be recovered at surgery.