Captured in 1969, this image depicts the right arm of a 6 month-old boy, who after having received a primary smallpox vaccination developed toxic epidermal necrolysis (TEN). This image was captured 5 days after he’d been vaccinated. See PHIL 3284, for a closer, earlier view of this lesion. He was treated with the synthetic corticosteroid, prednisone, and vaccinia immune globulin (VIG), and hospitalized for 32 days. He lost large areas of skin, but required no skin grafting.