ID#: 22175
Centers for Disease Control and Prevention (CDC) performs genome sequencing to compare the genetic sequences of vaccine viruses with those of circulating viruses. This is one way to assess how closely related the circulating influenza viruses are to the viruses the influenza vaccine is formulated to protect against.

CDC uses “Next Generation Sequencing” (NGS) methodologies that provide a tremendous amount of detail about each influenza genome. NGS techniques represent various high-throughput DNA sequencing strategies, whereby, millions to billions of DNA strands are sequenced in a highly parallel manner, dramatically improving throughput to understand sample complexity. This level of detail benefits decision-making with regard to vaccine composition, because it can help identify emerging changes in circulating flu viruses much earlier than before. Here, a scientist prepares a sequencer machine for a run.

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Content Provider(s): CDC/ Emily Cramer
Creation Date: 2017
Photo Credit: Videographer: Todd Jordan
Links: CDC - National Center for Immunization and Respiratory Diseases (NCIRD); Influenza (Flu)
CDC Organization
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Copyright Restrictions: None - This image is in the public domain and thus free of any copyright restrictions.