The infant pictured here, had been hospitalized due to a disseminated histoplasmosis infection. Note the areas of skin discoloration dispersed over all regions of the patient’s body, which are known as purpura, as well as other skin lesions, and the pen markings on the abdomen made during hospitalization indicating the enlargement of the infant's spleen and liver, known respectively as splenomegaly, and hepatomegaly. See PHIL 15361, and 19422, for additional views of this patient’s condition.
For some people, the symptoms of histoplasmosis will go away without treatment. However, prescription antifungal medication is needed to treat severe histoplasmosis in the lungs, chronic histoplasmosis, and infections that have spread from the lungs to other parts of the body (disseminated histoplasmosis). Itraconazole is one type of antifungal medication that’s commonly used to treat histoplasmosis. Depending on the severity of the infection and the person’s immune status, the course of treatment can range from 3 months to 1 year.