ID#: 19202
At the component level, this diagram illustrates what takes place microbiologically, during an indirect hemagglutination (IHA) inhibition test, which implements the herpes simplex virus (HSV) antigen in order to detect the presence of the HSV-specific antibody. Note that the upper portion of the diagram illustrates in a simplistic manner, the reactive interaction between the HSV-specific antibody, and the HSV antigen that induced the formation of an HSV antigen-antibody complex. The lower half of the diagram then shows how sheep red blood cells (RBCs) when sensitized, or bound, to the HSV antigen, cannot bind to the HSV antigen-antibody complex, and subsequently, there is no hemagglutination of the sheep RBCs, thereby, producing a positive test result.
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Content Provider(s): CDC/ Dr. F.T. Forrester
Creation Date: 1975
Photo Credit:
CDC Organization
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Copyright Restrictions: None - This image is in the public domain and thus free of any copyright restrictions.