ID#: 18903
This photomicrograph of an unknown tissue section, had been prepared using the Delafield's hematoxylin-eosin staining method, in order to best demonstrate the presence of intracellular Donovan bodies, which you can see here (a), inside a white blood cell (WBC). This is a pathognomonic finding for the sexually-transmitted disease, granuloma inguinale, also known as Donovanosis. Note the small, rounded inclusions lining the periphery of the intracellular vacuoles. Granuloma inguinale, or Donovanosis is caused by an organism that is difficult to culture, and diagnosis, therefore, requires visualization of dark-staining Donovan bodies on tissue crush preparation from a biopsy.
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Content Provider(s): CDC
Creation Date: 1977
Photo Credit:
CDC Organization
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