Skip directly to search Skip directly to A to Z list Skip directly to navigation Skip directly to page options Skip directly to site content


This image depicts a dorsal view of a patient’s hands, which exhibited a number of symptoms found in late congenital syphilis due to syphilitic bone disease that included osteoperiostitis, ulnar deviation of the middle fingers, and "du Bois sign", which involves a shortening of the little finger. Congenital syphilis occurs when a developing infant within the womb is infected by the spirochete microorganism, Treponema pallidum, as it receives blood by way of the placenta.
Additional Information:
Congenital syphilis is a condition with a wide spectrum of severity, and only severe cases are clinically apparent at birth. An infant or child (aged less than 2 years) may have signs such as hepatosplenomegaly, rash, condyloma lata, snuffles, jaundice (nonviral hepatitis), pseudoparalysis, anemia, or edema (nephrotic syndrome and/or malnutrition). An older child may have stigmata, e.g., interstitial keratitis, nerve deafness, anterior bowing of shins, and rhagades, or Clutton joints.
High Resolution: Click here for hi-resolution image (18.35 MB)
Content Providers(s):CDC/ Renelle Woodall
Creation Date:1969
Photo Credit:
Links:CDC – National Center for HIV, STD and TB Prevention Division of Sexually Transmitted Diseases – STD Prevention – Syphilis Fact
CDC – National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention; Division of STD Prevention; Sexually Transmitted Diseases (STDs); 2006 Treatment Guidelines: Congenital Syphilis
CDC Organization
Skip Navigation Links.

Skip Navigation Links.
Copyright Restrictions:None - This image is in the public domain and thus free of any copyright restrictions. As a matter of courtesy we request that the content provider be credited and notified in any public or private usage of this image.