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Description:This photomicrograph reveals the presence of numerous Pneumocystis jirovecii, formerly Pneumocystis carinii cysts, which were revealed in this Gram-Weigert-stained rat lung tissue sample.
The specific diagnosis is based on identification of P. jirovecii in bronchopulmonary secretions obtained as induced sputum, or bronchoalveolar lavage (BAL) material. In situations where these two techniques cannot be used, transbronchial biopsy or open lung biopsy may prove necessary. Microscopic identification of P. jirovecii trophozoites and cysts is performed with stains that demonstrate either the nuclei of trophozoites and intracystic stages (such as Giemsa) or the cyst walls (such as the silver stains). In addition, immunofluorescence microscopy using monoclonal antibodies can identify the organisms with higher sensitivity than conventional microscopy.
High Resolution: Click here for hi-resolution image (18.34 MB)
Content Providers(s):CDC/ Dr. Mae Melvin
Creation Date:1980
Photo Credit:
Links:CDC – Div. of Parasitic Diseases (DPDx); Pneumocystis infection
CDC – Emerging Infectious Diseases, Pneumocystis jirovecii in General Population”, by Francisco J. Medrano, et. al., Vol. 11, No. 2 – February, 2005, Research
CDC Organization
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Copyright Restrictions:None - This image is in the public domain and thus free of any copyright restrictions. As a matter of courtesy we request that the content provider be credited and notified in any public or private usage of this image.