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ID#:15083
Description:Processed using Dieterle’s silver stain, sometimes referred to as Pund’s method, under photomicrographic examination, this image reveals the presence of numerous Donovan bodies, displaying their characteristic morphology described as a closed safety-pin appearance.
Diagnosis of granuloma inguinale is based on the appearance of encapsulated bacilli called Donovan bodies. These are safety pin-shaped microorganisms that appear inside infected tissue cells under a microscope.

Granuloma Inguinale:

Clinical description:

A slowly progressive ulcerative disease of the skin and lymphatics of the genital and perianal area caused by infection with Calymmatobacterium granulomatis. A clinically compatible case would have one or more painless or minimally painful granulomatous lesions in the anogenital area.

Laboratory criteria for diagnosis:

Demonstration of intracytoplasmic Donovan bodies in Wright or Giemsa-stained smears or biopsies of granulation tissue

High Resolution: Click here for hi-resolution image (6.14 MB)
Content Providers(s):CDC/ Susan Lindsley
Creation Date:1977
Photo Credit:
Links:CDC - Case definitions for infectious conditions under public health surveillance, 1997, MMWR Morb Mortal Wkly Rep. 1997;46(No. RR-10).
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Copyright Restrictions:None - This image is in the public domain and thus free of any copyright restrictions. As a matter of courtesy we request that the content provider be credited and notified in any public or private usage of this image.

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