Diagnosis of granuloma inguinale is based on the appearance of encapsulated bacilli called Donovan bodies. These are safety pin-shaped microorganisms that appear inside infected tissue cells under a microscope.
A slowly progressive ulcerative disease of the skin and lymphatics of the genital and perianal area caused by infection with Calymmatobacterium granulomatis. A clinically compatible case would have one or more painless or minimally painful granulomatous lesions in the anogenital area.
Laboratory criteria for diagnosis:
Demonstration of intracytoplasmic Donovan bodies in Wright or Giemsa-stained smears or biopsies of granulation tissue