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ID#:14904
Description:At the component level, this diagram illustrates what takes place microbiologically during an indirect hemagglutination (IHA) inhibition test, which implements the herpes simplex virus (HSV) antigen in order to detect the presence of the HSV-specific antibody.
Note that the upper portion of the diagram illustrates in a simplistic manner, the negative interaction between the HSV-specific antibody, and a heterologous antigen, leaving the HSV antibody free to subsequently bind to sheep red blood cells (RBCs) that had been sensitized with HSV antigen. Had the HSV-specific antigen bound to the heterologous antigen, no hemagglutination of the sheep RBCs would have occurred. The results of this test indicate that there was no HSV antigen present in the initial sample, prior to its indirect addition by way of the sensitized sheep RBCs.
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Content Providers(s):CDC/ Dr. F.T. Forrester
Creation Date:1975
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Copyright Restrictions:None - This image is in the public domain and thus free of any copyright restrictions. As a matter of courtesy we request that the content provider be credited and notified in any public or private usage of this image.

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