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ID#:14903
Description:At the component level, this diagram illustrates two different direct hemagglutination reactions, a positive viral hemagglutination assay reaction (above), and a negative viral hemagglutination assay (HA) reaction (below). The former involves a hemagglutinating virus, while the latter involves the implementation of a non-hemagglutinating virus, and how each interacts “directly” with red blood cells.
Using the “direct” agglutination test the agglutinating antibodies on the surface of the viral particles, or virions, react directly with antigens on the surface of the erythrocytes, or RBCs, forming visible clumps of particles. Indirect, or passive, hemagglutination tests involve agglutinating antibodies on the viral particle surface reacting with antigens that have been passively coupled to carrier particles such as RBCs forming visible clumps.
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Content Providers(s):CDC/ Dr. F.T. Forrester
Creation Date:1975
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Copyright Restrictions:None - This image is in the public domain and thus free of any copyright restrictions. As a matter of courtesy we request that the content provider be credited and notified in any public or private usage of this image.

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