|Description:||Depicted here, is a dorsal view of a patient’s left foot, which exhibited pathologic changes indicative of a mycetoma, due to the cutaneous invasion of the Gram-positive Streptomyces somaliensis bacterial organisms.|
Mycetoma is a chronic, long standing, cutaneous infection whereupon, there is the formation of a deep dermal granulomatous inflammatory response that can, if left untreated, extend to the underlying muscle and bone.
Streptomyces species are aerobic actinomycetes best known for their production of antimicrobial substances. They infrequently cause human disease, most often manifesting as a localized, chronic suppurative infection of the skin and underlying soft tissue. Nonmycetomic infections caused by Streptomyces species are very rare.