|Description:||This PAS-stained photomicrograph of an unknown tissue specimen revealed the presence of three Coccidioides immitis spherules, which contain developing endospores.|
What are the symptoms of coccidioidomycosis?
About 60% of infections do not cause any symptoms. People who develop symptoms may experience a flu-like illness, with fever, cough, headache, rash and muscle aches. Most people make a full recovery, within weeks to months of symptom onset, but a small number of people may develop chronic pulmonary infection or widespread disseminated infection. When the infection spreads outside of the lungs, it most commonly results in skin lesions, central nervous system infection, such as meningitis, and bone and joint infection. Some people are at increased risk for developing disseminated infection: people of African-American, Asian or Filipino descent appear to be at increased risk, as do pregnant women during the third trimester and immunocompromised persons.