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Description:This photomicrograph depicts the results of a Tzanck test involving a tissue scraping of an active skin ulcer from a penile lesion, in what was diagnosed as a case of herpes progenitalis. In this particular view, you’ll note the presence of a multinucleated giant cell, also known as a Tzanck cell, in the center of this image.
The discovery of Tzanck cells alone will not be a conclusive finding in a diagnosis of herpes simplex, for these cells are also found in scraping from ulcers involved in varicella zoster virus (VZV) lesions, as well as the autoimmune disease pemphigus vulgaris, and human cytomegalovirus (HCMV) lesions.
High Resolution: Click here for hi-resolution image (10.04 MB)
Content Providers(s):CDC
Creation Date:1986
Photo Credit:
Links:CDC – National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Division of STD Prevention; Sexually Transmitted Diseases (STDs): Genital Herpes – CDC Fact Sheet
CDC Organization
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Copyright Restrictions:None - This image is in the public domain and thus free of any copyright restrictions. As a matter of courtesy we request that the content provider be credited and notified in any public or private usage of this image.