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Under a high magnification of 400X, this hematoxylin-eosin-stained (H&E) photomicrograph depicts the cytoarchitectural changes found in a liver tissue specimen extracted from a deceased yellow fever patient. Of importance, is the “presence of hepatocytes displaying polyvacuolar, and microvacuolar fatty changes at the edge of the zone of necrosis. These lesions were found to be associated with malnutrition, and a malarial infection.” See PHIL 2176, and 8239, depicting TEMs of the yellow fever virus.
From the booklet entitled, ”Yellow Fever: Positive and Differential Histopathology Diagnosis”, PHIL images 13001 through 13043 illustrate the findings encountered when performing a differential diagnoses comparing characteristics of liver cytoarchitecture in cases of yellow fever with viral hepatitis, Lassa fever, Marburg virus, Ebola virus, Dengue hemorrhagic fever, Congo-Crimean hemorrhagic fever, Rift Valley fever, and malnutrition.
High Resolution: Click here for hi-resolution image (18.26 MB)
Content Providers(s):Dr. Yves Robin and Dr. Jean Renaudet, Arbovirus Laboratory at the Pasteur Institute in Dakar, Senegal; World Health Organization
Creation Date:1980
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Links:© Copyright Notice: World Health Organization (WHO)
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Copyright Restrictions:Yes - This image is copyright protected. Any public or private use of this image is subject to prevailing copyright laws.Please contact the content provider of this image for permission requests.