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Description:From the “Illustrated Manual for the Recognition and Diagnosis of Certain Animal Diseases”, published in 1982, by the Mexico-United States Commission for the Prevention of Foot and Mouth Disease, captured during a swine's necropsy, this photograph compares the grossly-pathologic appearance of a spleen from a pig with an acute case of African swine fever (ASF) (top), to the spleen of a healthy, normal pig. Note the enlarged spleen, known as splenomegaly, appears twice as large as the normal spleen, and is friable, i.e., easily fragmented or torn apart, and in this state, is sometimes referred to as a “blackberry jam” spleen.
ASF is caused by an enzootic DNA virus belonging to the family Asfarviridae. “It is sensitive to lipid solvents and ortho-phenylphenol disinfectant, but is resistant to strong acids and alkalies. ASF virus causes hemadsorption of swine red blood cells (RBC) in infected leukocyte , i.e., white blood cell (WBC) cultures,” which means that the RBCs adhere to the infected WBCs. “Incubation is between 5 and 15 days, and symptomatology includes fever, depression, lachrymal discharge, cough, diarrhea, and dehydration. Organ pathology includes possible hemorrhages found on the epicardium and endocardium; lymph nodes may be hemorrhagic; enlargement of the spleen; petechial hemorrhages of the kidneys and urinary bladder occasionally are found.”
High Resolution: Click here for hi-resolution image (18.35 MB)
Content Providers(s):CDC/ Dr. Jerry J. Callis, PIADC/Dr. Brian W.J. Mahy, CDC
Creation Date:1982
Photo Credit:
Links:Plum Island Animal Disease Center (PIADC) - United States Department of Agriculture (USDA) – Agricultural Research Service (ARS) – U.S. Department of Homeland Security
CDC Organization
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Copyright Restrictions:None - This image is in the public domain and thus free of any copyright restrictions. As a matter of courtesy we request that the content provider be credited and notified in any public or private usage of this image.