|Description:||This image depicts a close view of the right eye of a patient revealing the pathologic changes in her cornea known as interstitial corneal keratitis, which was due to a congenital syphilitic infection, and is a chronic progressive keratitis of the corneal stroma, i.e., connective tissue matrix, often resulting in blindness and frequently associated with congenital syphilis.|
Congenital syphilis, is a condition caused by infection in utero with Treponema pallidum. A wide spectrum of severity exists, and only severe cases are clinically apparent at birth. An infant or child (aged less than 2 years) may have signs such as hepatosplenomegaly, rash, condyloma lata, snuffles, jaundice (nonviral hepatitis), pseudoparalysis, anemia, or edema (nephrotic syndrome and/or malnutrition). An older child may have stigmata (e.g., interstitial keratitis, nerve deafness, anterior bowing of shins, frontal bossing, mulberry molars, Hutchinson teeth, saddle nose, rhagades, or Clutton joints).