|Description:||This 1965 photograph depicted the volar surface of an extended right arm of a patient who’d been ill with leishmaniasis, having been infected with Leishmania sp. protozoa, which had manifested itself as a cutaneous form of the disease.|
Human leishmanial infections can result in 2 main forms of disease, cutaneous leishmaniasis, as was the case here, and visceral leishmaniasis (kala-azar). The factors determining the form of disease include leishmanial species, geographic location, and immune response of the host. Cutaneous leishmaniasis is characterized by one or more cutaneous lesions on areas where sand flies have fed. Persons who have cutaneous leishmaniasis have one or more sores on their skin. The sores can change in size and appearance over time. They often end up looking somewhat like a volcano, with a raised edge and central crater. A scab covers some sores. The sores can be painless or painful. Some people have swollen glands near the sores, for example, in the armpit, if the sores are on the arm or hand.