|Description:||This photograph depicted a single, large colony of Acremonium falciforme fungal organisms, which had been grown on Sabouraud dextrose agar. A. falciforme colonies feature a variety of characteristics including a folded or, as it was in this case, a flat surface, and often have a raised center. Early colonies exhibit a soft, velvety texture, which becomes more cottony as the colony ages. Colonial coloration ranges from white, as seen here, to pale gray or pink.|
A. falciforme fungus is a known causative agent for the disease in humans known as eumycotic white grain mycetoma, a chronic granulomatous inflammatory condition mainly affecting the cutaneous and subcutaneous tissues, but has been found to also infect the eye (keratitis), nails (onychomycosis), and if systemically disseminated, can infect the heart (endocarditis), brain (meningitis), bones (osteomyelitis), and abdominal cavity (peritonitis). Immunocompromised individuals, such as those with AIDS, or undergoing chemo- or organ transplant therapy, are most susceptible due to the opportunistic nature of this organism.