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Description:This transmission electron microscopic (TEM) image revealed the presence of a large paramyxovirus virion and numerous external viral nucleocapsids, which in this instance, was responsible for a case of the mumps. Paramyxoviruses are members of the family, Paramyxoviridae, and those that cause mumps in humans belong to the genus, Rubulavirus. The virus itself can present itself in a number of morphologic shapes, including spherical, and stand-like, or filamentous, ranging from 150nm to 200nm in diameter, and 1000nm to 10000nm in length. At its core lies a non-segmented, negative-sense RNA genome.
Onset of illness is usually nonspecific: fever, headache, malaise, myalgia, and anorexia. In unvaccinated populations, an estimated 30%-40% of mumps infections produce typical parotitis, as many as 20% of infections are asymptomatic, and up to 50% are associated with nonspecific or primarily respiratory symptoms. Although mumps is generally a mild and self-limited disease, complications of mumps infection can include deafness; orchitis, oophoritis, or mastitis (inflammation of the testicles, ovaries or breasts, respectively); pancreatitis; meningitis/encephalitis; and spontaneous abortion. With the exception of deafness, these complications are more frequent in adults than in children.
High Resolution: Click here for hi-resolution image (3.44 MB)
Content Providers(s):CDC/ Dr. Fred Murphy
Creation Date:1975
Photo Credit:
Links:CDC - National Center for Immunization and Respiratory Diseases; Mumps Vaccination
CDC – Nat. Center for Preparedness, Detection, and Control of Infectious Diseases; Div. of Global Migration and Quarantine; Travelers’ Health: Yellow Book: Mumps
CDC Organization
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Copyright Restrictions:None - This image is in the public domain and thus free of any copyright restrictions. As a matter of courtesy we request that the content provider be credited and notified in any public or private usage of this image.