|Description:||This transmission electron microscopic (TEM) image revealed the presence of a large paramyxovirus virion and numerous external viral nucleocapsids, which in this instance, was responsible for a case of the mumps. Paramyxoviruses are members of the family, Paramyxoviridae, and those that cause mumps in humans belong to the genus, Rubulavirus. The virus itself can present itself in a number of morphologic shapes, including spherical, and stand-like, or filamentous, ranging from 150nm to 200nm in diameter, and 1000nm to 10000nm in length. At its core lies a non-segmented, negative-sense RNA genome.|
Onset of illness is usually nonspecific: fever, headache, malaise, myalgia, and anorexia. In unvaccinated populations, an estimated 30%-40% of mumps infections produce typical parotitis, as many as 20% of infections are asymptomatic, and up to 50% are associated with nonspecific or primarily respiratory symptoms. Although mumps is generally a mild and self-limited disease, complications of mumps infection can include deafness; orchitis, oophoritis, or mastitis (inflammation of the testicles, ovaries or breasts, respectively); pancreatitis; meningitis/encephalitis; and spontaneous abortion. With the exception of deafness, these complications are more frequent in adults than in children.