ID#: 10156
This photomicrograph depicted details displayed by a specimen consisting of scrapings of formalin fixed lung tissue from a Knoxville patient with a fatal pneumonia due to Legionnaires’ disease. A fluorescent antibody stain was implemented, consisting of a Legionnaire #1 conjugate, at a dilution ratio of 1:16. In this case, an antibody with an affinity to L. pneumophila bacteria, was conjugated with a fluorochrome, which is a fluorescent dye, e.g. fluorescein isothiocyanate. The presence of the Legionella bacteria was evidenced, when the antibody-dye complex became bound to the bacterial cell wall, and fluoresced when exposed to light.
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Content Provider(s): CDC/ Dr. William Cherry
Creation Date: 1978
Photo Credit:
CDC Organization
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Copyright Restrictions: None - This image is in the public domain and thus free of any copyright restrictions.