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Description:This micrograph depicted details displayed by a specimen consisting of scrapings of formalin fixed lung tissue from a Knoxville patient with a fatal pneumonia due to Legionnaires’ disease. A fluorescent antibody stain was implemented consisting of a Legionnaire #1 conjugate at a dilution ration of 1:16. In this case, an antibody with an affinity to L. pneumophila bacteria, was conjugated with a fluorochrome, which is a fluorescent dye, e.g. fluorescein isothiocyanate. The presence of the Legionella bacteria was evidenced when the antibody-dye complex became bound to the bacterial cell wall, and fluoresced when exposed to light.
What are the symptoms of Legionnaires’ disease?

Legionnaires' disease can have symptoms like many other forms of pneumonia, so it can be hard to diagnose at first. Signs of the disease can include: a high fever, chills, and a cough. Some people may also suffer from muscle aches and headaches. Chest X-rays are needed to find the pneumonia caused by the bacteria, and other tests can be done on sputum (phlegm), as well as blood or urine to find evidence of the bacteria in the body.

Symptoms usually begin 2-14 days after being exposed to the bacteria.

A milder infection caused by the same type of Legionella bacteria is called Pontiac Fever, symptoms of which usually last for 2-5 days and may also include fever, headaches, and muscle aches; however, there is no pneumonia. Symptoms resolve on their own without treatment and without causing further problems.

Pontiac Fever and Legionnaires’ disease may also be called “Legionellosis” separately or together.

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Content Providers(s):CDC/ Dr. William Cherry
Creation Date:1978
Photo Credit:
Links:CDC – Div. of bacterial and Mycotic Diseases – Legionellosis: Legionnaire's Disease (LD) and Pontiac Fever
CDC Organization
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Copyright Restrictions:None - This image is in the public domain and thus free of any copyright restrictions. As a matter of courtesy we request that the content provider be credited and notified in any public or private usage of this image.