|Description:||Magnified 980X, this photomicrograph depicted numbers of Cryptococcus neoformans fungi, the etiologic agents responsible for the disease “cryptococcosis”. This slide was created from a liver specimen, and stained using the periodic acid-Schiff staining technique.|
Initially a pulmonary infection, cryptococcosis can become a systemically-disseminated disease, which was the reason for their presence in this liver specimen. It can also lead to meningoencephalitis, an inflammation of the brain and its coverings, known as meninges. Persons with HIV, or who are immunocompromised undergoing chemotherapy, are most susceptible.