ID#: 5308
This represents the seventh slide in a series highlighting the history, chemistry, and uses of ricin, a highly toxic poison made from castor beans. The slide, entitled, “Ricin Molecule”, describes the molecule as a 66kDa heterodimer, bonded by a disulfide bridge, the B-chain (34kDa) binds to cell surface receptors, while the toxin-receptor complex is taken into the cell, the A-chain ((32kDa) has endonuclease activity, and inhibits DNA replication and protein synthesis at low levels (cytotoxin). This presentation is copyrighted by Dr. Jonathan Burstein, MD, Anthony J. Carbone, MD, MPH, of the Harvard Center for Public Health Preparedness, Harvard School of Public Health.
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Content Provider(s): CDC/ Dr. Jonathan Burstein, MD/ Anthony J. Carbone MD MPH
Creation Date: 2003
Photo Credit:
CDC Organization
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