ID#: 15737
At the component level, this diagram illustrates what takes place microbiologically during an indirect hemagglutination (IHA) inhibition test, which implements the herpes simplex virus (HSV) antigen in order to detect the presence of the HSV-specific antibody. Note that the upper portion of the diagram illustrates in a simplistic manner, the components involved in the positive agglutination reaction between the humoral HSV-specific antibody and sheep red blood cells (RBCs) sensitized with HSV antigen. The result is clumping, or agglutination of the RBCs. Below, you will note the negative reaction involving HSV-sensitized RBCs in the presence of heterologous antibodies, which leads to no agglutination of the RBCs.
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Content Provider(s): CDC/ Dr. F.T. Forrester
Creation Date: 1975
Photo Credit:
CDC Organization
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Copyright Restrictions: None - This image is in the public domain and thus free of any copyright restrictions.