ID#: 14765
Under a magnification of 1000X, this photomicrograph of a hematoxylin-eosin (H&E)-stained vaginal tissue biopsy specimen, revealed some of the histopathologic changes indicative of adenocarcinoma of the vagina. This case involved a teenage girl, and it was believed that the onset of her cancer might have been because the patient’s mother had taken diethylstilbestrol (DES) while pregnant, as a treatment to avoid a possible spontaneous abortion. DES daughters are at increased risk for a wide range of abnormalities involving the Müllerian-derived portion of the genital tract, including clear cell adenocarcinoma (CCA) of the vagina and cervix, genital malformations, infertility and adverse pregnancy outcomes. In addition, DES daughters may be at increased risk for development of cervical dysplasia.
High Resolution: Click here for hi-resolution image (18.38 MB)
Content Provider(s): CDC/ A. Elizabeth Plott, C.T.(ASCP)
Creation Date: 1975
Photo Credit:
CDC Organization
Skip Navigation Links.

Skip Navigation Links.
Copyright Restrictions: None - This image is in the public domain and thus free of any copyright restrictions.