|Description:||Using immunohistochemical (IHC) technique, this photomicrograph revealed some of the cytoarchitectural histopathologic changes associated with a Nipah virus infection, in this case affecting a human patient, resulting in the formation of a syncytial cell, i.e., giant, multinucleated endothelial cell, in the center of the image.|
Infection with Nipah virus has been associated with an encephalitis (inflammation of the brain) characterized by fever and drowsiness and more serious central nervous system disease, such as coma, seizures, and inability to maintain breathing.
Nipah virus, a member of the family Paramyxoviridae, is related but not identical to Hendra virus. Nipah virus was initially isolated in 1999 upon examining samples from an outbreak of encephalitis and respiratory illness among adult men in Malaysia and Singapore. Its name originated from Sungai Nipah, a village on the Malaysian Peninsula where pig farmers became ill with encephalitis.