|Description:||This image depicts the perineal region of a male patient, who’d presented with what was described as eroded, moist, papular intertrigo, due to what was diagnosed as a case of secondary syphilis. Intertrigo is an inflamed area of a skin fold where two skin surfaces touch one another, such as here, in the gluteal cleft between the buttocks.|
The secondary stage of syphilis is characterized by the manifestation of a skin rash and mucous membrane lesions. This stage typically starts with the development of a rash on one or more areas of the body. The rash usually does not cause itching.
Rashes associated with secondary syphilis can appear as the chancre is healing or several weeks after the chancre has healed. The characteristic rash of secondary syphilis may appear as rough, red, or reddish brown spots both on the palms of the hands and the bottoms of the feet. However, rashes with a different appearance may occur on other parts of the body, sometimes resembling rashes caused by other diseases. Sometimes rashes associated with secondary syphilis are so faint that they are not noticed. In addition to rashes, symptoms of secondary syphilis may include fever, swollen lymph glands, sore throat, patchy hair loss, headaches, weight loss, muscle aches, and fatigue. The signs and symptoms of secondary syphilis will resolve with or without treatment, but without treatment, the infection will progress to the latent and possibly late stages of disease.