|Description:||This 1964 image depicted a Tehrani man who was being treated for what was diagnosed as pemphigus vulgaris. He presented with a painful, long-standing intraoral lesions of 3 years duration. In this particular view, the lesions can be seen on the interior surface of his left cheek.|
See PHIL 12570, 12572 for other views depicting lesions on the patient’s lower lip and gums, and tongue, respectively, as well as 12573, for another view of the left cheek interior. The patient also had painful lesions in the perineal region. The intraoral lesions were covered with a grayish-white membrane, which when peeled away, left a fiery red sore. These were preceded by mucosal eruptions, as were lesions elsewhere on his body.
Pemphigus vulgaris (PV) is categorized as an autoimmune disorder, which is chronic, and though not “curable”, is controllable through the use of immunosuppressive therapy. A patient’s own antibodies begin attacking the cells within his own skin and mucous membranes, thereby, leading to the formation of chronic lesions, usually in the intraoral region, but can manifest themselves elsewhere on the body, i.e., the perineum.