|Description:||Under a magnification of 1125X, this PAS-stained (periodic-acid-Schiff) photomicrograph of a Florida dolphin tissue sample, revealed some of the histopathologic cytoarchitectural changes associated with what was determined to be a case of lobomycosis due to the fungus, Lacazia loboi, formerly known as Loboa loboi. Usually, lobomycosis is seen in humans and dolphins.|
Lobomycosis is also known by the names Lobo’s disease, and lacaziosis, and is a chronic inflammatory fungal infection. Histopathologic characteristics include the presence of large numbers of yeast-like cells, which morphologically are large, ranging in size from 5µm to 12µm, and are thick-walled. As seen in this case, you’ll note the presence of tubular interconnection between these cells. The use of PAS stain is standard when micrographically studying this fungal organism, as well as Gomori, Grocott and Gridley silver stains.