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PHIL Image 12163
 
ID#:12163
Description:This photomicrograph depicts numerous Gram-positive asporogenous, rod-shaped, Corynebacterium diphtheriae bacteria.

The incubation period is 2-5 days (range 1-10 days), and the onset of symptoms is gradual. Early symptoms of respiratory diphtheria include malaise, sore throat, difficulty in swallowing, loss of appetite, and a mild fever (rarely >101° F). If the larynx is involved, the affected person may become hoarse. Within 2–3 days, an adherent, gray membrane forms over the mucous membrane of the tonsils, pharynx, or both. Attempts to remove the membrane cause bleeding. In severe cases of respiratory diphtheria, cervical lymphadenopathy and soft tissue swelling in the neck give rise to a “bull-neck” appearance. Extensive membrane formation may result in life-threatening or fatal airway obstruction.

Diphtheria toxin can cause serious systemic complications including myocarditis and neuropathies, if it is absorbed from the site of infection. Cutaneous and nasal diphtheria are localized infections that are rarely associated with systemic toxicity. The case-fatality rate of respiratory diphtheria is 5%-10%.

High Resolution:Right click here and select "Save Target As..." for hi-resolution image (13.19 MB)
Content Providers(s):CDC/ Graham Heid
Creation Date:1965
Photo Credit:
Links:
  • CDC - National Center for Immunization and Respiratory Diseases: Division of Bacterial Diseases: Diphtheria
    Categories:
    CDC Organization

    MeSH
    tree picture Chemicals and Drugs
    tree picture tree picture Enzymes and Coenzymes
    tree picturetree picture tree picture Enzymes
    tree picturetree picturetree picture tree picture Transferases
    tree picturetree picturetree picturetree picture tree picture Glycosyltransferases
    tree picturetree picturetree picturetree picturetree picture tree picture Pentosyltransferases
    tree picturetree picturetree picturetree picturetree picturetree picture tree picture ADP Ribose Transferases
    tree picturetree picturetree picturetree picturetree picturetree picturetree picture tree picture Diphtheria Toxin
    tree picture tree picture Immunologic and Biological Factors
    tree picturetree picture tree picture Biological Factors
    tree picturetree picturetree picture tree picture Toxins
    tree picturetree picturetree picturetree picture tree picture Bacterial Toxins
    tree picturetree picturetree picturetree picturetree picture tree picture Diphtheria Toxin
    tree picturetree picture tree picture Biological Products
    tree picturetree picturetree picture tree picture Antitoxins
    tree picturetree picturetree picturetree picture tree picture Diphtheria Antitoxin
    tree picturetree picturetree picture tree picture Vaccines
    tree picturetree picturetree picturetree picture tree picture Bacterial Vaccines
    tree picturetree picturetree picturetree picturetree picture tree picture Diphtheria-Tetanus Vaccine
    tree picturetree picturetree picturetree picturetree picture tree picture Diphtheria-Tetanus-acellular Pertussis Vaccines
    tree picturetree picturetree picturetree picturetree picture tree picture Diphtheria-Tetanus-Pertussis Vaccine
    tree picturetree picturetree picturetree picturetree picture tree picture Pertussis Vaccine
    tree picturetree picturetree picturetree picturetree picturetree picture tree picture Diphtheria-Tetanus-acellular Pertussis Vaccines
    tree picturetree picturetree picturetree picture tree picture Toxoids
    tree picturetree picturetree picturetree picturetree picture tree picture Diphtheria Toxoid
    tree picturetree picturetree picturetree picturetree picturetree picture tree picture Diphtheria-Tetanus Vaccine
    tree picturetree picturetree picturetree picturetree picturetree picture tree picture Diphtheria-Tetanus-acellular Pertussis Vaccines
    tree picturetree picturetree picturetree picturetree picturetree picture tree picture Diphtheria-Tetanus-Pertussis Vaccine
    tree picturetree picturetree picturetree picturetree picture tree picture Tetanus Toxoid
    tree picturetree picturetree picturetree picturetree picturetree picture tree picture Diphtheria-Tetanus-acellular Pertussis Vaccines
    tree picturetree picturetree picturetree picture tree picture Vaccines, Combined
    tree picturetree picturetree picturetree picturetree picture tree picture Diphtheria-Tetanus Vaccine
    tree picturetree picturetree picturetree picturetree picture tree picture Diphtheria-Tetanus-acellular Pertussis Vaccines
    tree picturetree picturetree picturetree picture tree picture Vaccines, Subunit
    tree picturetree picturetree picturetree picturetree picture tree picture Vaccines, Acellular
    tree picturetree picturetree picturetree picturetree picturetree picture tree picture Diphtheria-Tetanus-acellular Pertussis Vaccines
    tree picturetree picture tree picture Immunologic Factors
    tree picturetree picturetree picture tree picture Antibodies
    tree picturetree picturetree picturetree picture tree picture Antitoxins
    tree picturetree picturetree picturetree picturetree picture tree picture Diphtheria Antitoxin
    tree picture Diseases
    tree picture tree picture Bacterial Infections and Mycoses
    tree picturetree picture tree picture Bacterial Infections
    tree picturetree picturetree picture tree picture Gram-Positive Bacterial Infections
    tree picturetree picturetree picturetree picture tree picture Actinomycetales Infections
    tree picturetree picturetree picturetree picturetree picture tree picture Actinomycosis
    tree picturetree picturetree picturetree picturetree picture tree picture Corynebacterium Infections
    tree picturetree picturetree picturetree picturetree picturetree picture tree picture Diphtheria
    tree picture Organisms
    tree picture tree picture Bacteria
    tree picturetree picture tree picture Gram-Positive Bacteria
    tree picturetree picturetree picture tree picture Actinobacteria
    tree picturetree picturetree picturetree picture tree picture Actinomycetales
    tree picturetree picturetree picturetree picturetree picture tree picture Corynebacterium
    tree picturetree picturetree picturetree picturetree picturetree picture tree picture Corynebacterium diphtheriae
    tree picturetree picturetree picture tree picture Gram-Positive Rods
    tree picturetree picturetree picturetree picture tree picture Gram-Positive Asporogenous Rods
    tree picturetree picturetree picturetree picturetree picture tree picture Gram-Positive Asporogenous Rods, Irregular
    tree picturetree picturetree picturetree picturetree picturetree picture tree picture Corynebacterium
    tree picturetree picturetree picturetree picturetree picturetree picturetree picture tree picture Corynebacterium diphtheriae
    Copyright Restrictions:None - This image is in the public domain and thus free of any copyright restrictions. As a matter of courtesy we request that the content provider be credited and notified in any public or private usage of this image.
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