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11821

PHIL Image 11821

ID#:11821
Description:This Giemsa-stained light photomicrograph revealed the presence of two Trypanosoma brucei parasites, which were found in a blood smear.

Humans are the main reservoir for Trypanosoma brucei gambiense, but this species can also be found in animals. Wild game animals are the main reservoir of T. b. rhodesiense.

Geographic Distribution:

T. b. gambiense is found in foci in large areas of West and Central Africa. The distribution of T. b. rhodesiense is much more limited, with the species found in East and Southeast Africa.

During a blood meal on the mammalian host, an infected tsetse fly (genus Glossina) injects metacyclic trypomastigotes into skin tissue. The parasites enter the lymphatic system and pass into the bloodstream. Inside the host, they transform into bloodstream trypomastigotes, are carried to other sites throughout the body, reach other blood fluids (e.g., lymph, spinal fluid), and continue the replication by binary fission. The entire life cycle of African trypanosomes is represented by extracellular stages. The tsetse fly becomes infected with bloodstream trypomastigotes when taking a blood meal on an infected mammalian host. In the fly’s midgut, the parasites transform into procyclic trypomastigotes, multiply by binary fission, leave the midgut, and transform into epimastigotes. The epimastigotes reach the fly’s salivary glands and continue multiplication by binary fission. The cycle in the fly takes approximately 3 weeks. See PHIL 3384 for a life cycle diagram.

High Resolution:Right click here and select "Save Target As..." for hi-resolution image (1.11 MB)
Content Providers(s):CDC/ Blaine Mathison
Creation Date:
Photo Credit:
Links:
  • CDC – Nat. Center for Infectious Diseases (NCID); Div. of Parasitic Diseases (DPDx); Trypanosomiasis, Africa
    Categories:
    CDC Organization

    MeSH
    tree picture Anatomy
    tree picture tree picture Cells
    tree picturetree picture tree picture Blood Cells
    tree picture tree picture Hemic and Immune Systems
    tree picturetree picture tree picture Blood
    tree picturetree picturetree picture tree picture Blood Cells
    tree picture Diseases
    tree picture tree picture Animal Diseases
    tree picturetree picture tree picture Rodent Diseases
    tree picture tree picture Hemic and Lymphatic Diseases
    tree picturetree picture tree picture Hematologic Diseases
    tree picture tree picture Parasitic Diseases
    tree picturetree picture tree picture Protozoan Infections
    tree picturetree picturetree picture tree picture Sarcomastigophora Infections
    tree picturetree picturetree picturetree picture tree picture Mastigophora Infections
    tree picturetree picturetree picturetree picturetree picture tree picture Trypanosomiasis
    tree picture Organisms
    tree picture tree picture Animals
    tree picturetree picture tree picture Chordata
    tree picturetree picturetree picture tree picture Vertebrates
    tree picturetree picturetree picturetree picture tree picture Mammals
    tree picturetree picturetree picturetree picturetree picture tree picture Rodentia
    tree picturetree picturetree picturetree picturetree picturetree picture tree picture Muridae
    tree picturetree picturetree picturetree picturetree picturetree picturetree picture tree picture Rats
    tree picturetree picture tree picture Invertebrates
    tree picturetree picturetree picture tree picture Arthropods
    tree picturetree picturetree picturetree picture tree picture Insects
    tree picturetree picturetree picturetree picturetree picture tree picture Fleas
    tree picturetree picturetree picture tree picture Protozoa
    tree picturetree picturetree picturetree picture tree picture Sarcomastigophora
    tree picturetree picturetree picturetree picturetree picture tree picture Mastigophora
    tree picturetree picturetree picturetree picturetree picturetree picture tree picture Zoomastigophora
    tree picturetree picturetree picturetree picturetree picturetree picturetree picture tree picture Kinetoplastida
    tree picturetree picturetree picturetree picturetree picturetree picturetree picturetree picture tree picture Trypanosomatina
    tree picturetree picturetree picturetree picturetree picturetree picturetree picturetree picturetree picture tree picture Trypanosoma
    tree picturetree picturetree picturetree picturetree picturetree picturetree picturetree picturetree picturetree picture tree picture Trypanosoma brucei brucei
    Copyright Restrictions:None - This image is in the public domain and thus free of any copyright restrictions. As a matter of courtesy we request that the content provider be credited and notified in any public or private usage of this image.
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    This page last reviewed: Mar. 18 2005
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